Faculty
Pathobiology and Mechanisms of Disease
Cory Abate-Shen, PhD
Research Interests: Molecular mechanisms of cancer development, Genitourinary cancer development
Address: ICRC 217A
Phone: 212-851-4731
Email: cabateshen@columbia.edu
Swarnali Acharyya, PhD
Research Interests: Exploring mechanisms of drug resistance and cancer metastasis
Address: ICRC 402B
Phone: 212-851-4791
Email: sa3141@icg.cpmc.columbia.edu
Dritan Agalliu, PhD
Research Interests: Dynamic Imaging of the CNS Vasculature, CNS and Retina Vascular Biology , Blood-Brain Barrier Biology, Neuroimmunology, Models of Psychiatric Disorders
Address: BB 310
Phone: 212-305-0323
Email: da191@cumc.columbia.edu
Rando Allikmets, PhD
Research Interests: Genetic studies of Mendelian and complex eye diseases (Stargardt macular dystrophy, Macular Telangiectasia, age-related macular degeneration, etc.) , Development of microarray-based and next generation sequencing-based diagnostic applications for eye diseases., Gene- and small molecule therapy for retinal disorders
Address: Harkness Eye Institute 202
Phone: 212-305-8989
Email: rla22@columbia.edu
Ottavio Arancio, MD, PhD
Research Interests: Synapses and Circuits, Biophysics/Ion Channels, Neural Degeneration and Repair, Neurobiology of Learning and Memory, Neurobiology of Disease
Address: P&S 12-420D
Phone: 212-342-0533
Email: oa1@cumc.columbia.edu
Edmund Au, PhD
Research Interests: Cell Lineage Specification , Neuronal Migration , Synaptic Specificity, Models of Psychiatric Illness
Address: BB 1411A
Phone: 212-305-0406
Email: ea2515@cumc.columbia.edu
Richard Axel, MD
Research Interests: Sensory Physiology, Neurogenetics, Synapses and Circuits
Address: JLGSC L8-001
Phone: 212-853-1006
Email: ra27@columbia.edu
Richard Baer, PhD
Research Interests: The pathogenesis of hereditary breast cancer
Address: ICRC 503A
Phone: 212-851-5275
Email: rb670@columbia.edu
Jonathan Barasch, MD, PhD
Research Interests: Discovering the mechanisms that produce the epithelial phenotype during the conversion of mesenchymal cells
Address: P&S 10-445
Phone: 212-305-1890
Email: jmb4@columbia.edu
Francesca Bartolini, PhD
Research Interests: Molecular and cellular biology of neurodegeneration; the regulation and functioin of the microtubule cytoskeleton at synapse
Address: P&S 14-460
Phone: 212-305-7299
Email: fb2132@cumc.columbia.edu
Uttiya Basu, PhD
Research Interests: RNA surveillance, noncoding RNA processing and DNA alteration events in lymphocytes
Address: HHSC 1308
Phone: 212-305-1815
Email: ub2121@columbia.edu
Elizabeth Bradshaw, PhD
Research interest: Translational and Computational Neuro-immunology
Address: P&S 5-420A
Phone: 212-305-3609
Email: emb2280@cumc.columbia.edu
Julie Canman, PhD
Research Interests: Molecular regulation of cell division and mechanisms of diversity during cytokinesis
Address: P&S 14-453
Phone: 212-305-5017
Email: jcc2210@columbia.edu
Peter Canoll, MD, PhD
Research Interests: Mechanisms of glioma growth and invasion
Address: ICRC 1001
Phone: 212-851-4632
Email: pc561@columbia.edu
Christine Chio, PhD
Research Interests: Preclinical therapeutics in genetically engineered mouse models of pancreatic cancer, Redox biology, Cancer metabolism, Ex vivo 3D organoid platforms to study pancreatic cancer
Address: ICRC 505
Phone: 212-851-4967
Email: ic2445@cumc.columbia.edu
Eunhee Choi, PhD
Research Interests: to delineate mechanisms underlying the mutual regulation between cell division and metabolism by combining mouse genetics, cell biology, biochemistry and cryo-EM structure.
Address: P&S 14-509
Phone: 212-305-1381
Email: ec3477@cumc.columbia.edu
Lorraine Clark, PhD
Research Interests: Genetics of neurological and neurodegenerative disease, Personalized genomic medicine, Human Genetics
Address: Russ Berrie 307
Phone: 212-851-5403
Email: lc654@columbia.edu
Piero Dalerba, MD
Research Interests: Application of single-cell technologies for the analysis of tissue cell composition. Identification and clinical development of novel predictive biomarkers to guide therapeutic algorithm design in human colon and breast cancer
Address: ICRC 505A
Phone: 212-851-4913
Email: pdd2109@columbia.edu
Riccardo Dalla-Favera, MD
Research Interests: Molecular genetics of cancer; molecular pathogenesis of lymphoma and leukemia; genetic control in lymphoid tissue development
Address: ICRC 508
Phone: 212-851-5273
Email: rd10@columbia.edu
Claudia Doege, MD
Research interest: Molecular mechanisms of human obesity, patient-specific disease modeling, human stem cell-derived hypothalamic neurons, genome editing
Address: Russ Berrie 615
Phone: 000-000-0000
Email: cad2114@cumc.columbia.edu
Dietrich Egli, PhD
Research Interests: Pluripotent stem cell
Address: RB 607B
Phone: 000-000-0000
Email: de2220@cumc.columbia.edu
Wassim Elyaman, PhD
Research Interests: Translational and Computational Neuro-immunology
Address: PH 19
Phone: 212-305-4759
Email: we2152@cumc.columbia.edu
Qing Fan, PhD
Research Interests: Structural biology, Cell surface receptor - ligand recognition
Address: PH 7W 318
Phone: 212-342-0115
Email: qf13@cumc.columbia.edu
Amin Ghabrial, PhD
Research Interests: Regulation of tube morphogenesis using novel optogenetic tools, as well as the further elaboration of the CCM3/GckIII pathway
Address: P&S 15-421
Phone: 212-305-8171
Email: asg2236@cumc.columbia.edu
James Goldman, MD, PhD
Research Interests: Cell Specification and Differentiation, Stem Cell Biology, Glial Development and Pathology, Tuberous Sclerosis/Epilepsy/Autism Spectrum Disorders
Address: P&S 15-405
Phone: 212-305-3554
Email: jeg5@cumc.columbia.edu
Wei Gu, PhD
Research Interests: P53 in tumor suppression and aging
Address: ICRC 609A
Phone: 212-851-5282
Email: wg8@columbia.edu
Gregg Gundersen, PhD
Research Interests: The regulation and function of the microtubule cytoskeleton
Address: P&S 15-402
Phone: 212-305-1899
Email: ggg1@columbia.edu
Rebecca Haeusler, PhD
Research Interests: Understand the development of pro-atherogenic metabolic abnormalities in the natural history of diabetes and the metabolic syndrome
Address: Russ Berrie 303A
Phone: 212-851-4899
Email: rah2130@cumc.columbia.edu
Ulrich Hengst, PhD
Research Interests: Neural Degeneration and Repair, Axon Pathfinding and Synaptogenesis, Cellular/Molecular/Developmental Neuroscience
Address: BB 1210A
Phone: 212-305-9334
Email: uh2112@cumc.columbia.edu
Eldad Hod, MD
Research Interests: Using in vitro systems, mouse models, and human studies to investigate important problems relating to red blood cell transfusion and iron biology, particularly related to refrigerated storage, iron deficiency, hemolytic transfusion reactions, red blood cell senescence, and phagocytosis
Clinical Trials
Address: P&S 14-434
Phone: 212-342-5648
Email: eh2217@cumc.columbia.edu
Krystalyn Hudson, PhD
Research Interests: immune response to red blood cells
Address: P&S 14-511
Phone: 212-305-6944
Email: keh2197@cumc.columbia.edu
Minah Kim, PhD
Research Interests: to understand the molecular mechanisms that drive immune and vascular changes in order to overcome the limitation of current anti-angiogenic therapy and immunotherapy.
Address: P&S 14-401
Phone: 212-305-1986
Email: mk4242@cumc.columbia.edu
Tae-Wan Kim, PhD
Research Interests: Neurogenetics, Neural Degeneration and Repair, Disease
Address: P&S 12-430
Phone: 212-305-5786
Email: twk16@cumc.columbia.edu
Ronald Liem, PhD
Research Interests: Neural Degeneration and Repair, Cellular/Molecular/Developmental Neuroscience
Address: P&S 15-421
Phone: 212-305-4078
Email: rkl2@columbia.edu
Fangming Lin, MD, PhD
Research Interests: Kidney injury and repair
Address: P&S 9-401B
Phone: 212-305-0793
Email: fl2300@columbia.edu
Ian Lipkin, MD
Research Interests: Immunopathogenesis and infectious diseases
Address: MSPH 1801
Phone: 212-342-9033
Email: wil2001@columbia.edu
Xiaoxiao Shawn Liu, PhD
Research Interests: Epigenome in physiology and disease
Address: Russ Berrie 403
Phone: 212-851-5340
Email: sl4738@cumc.columbia.edu
Gustavo Maegawa, MD, PhD
Research Interests: lysosomal diseases
Address: CHN 7
Phone:
Email: gm3025@cumc.columbia.edu
Carol Mason, PhD
Research Interests: Synapses and Circuits, Axon Pathfinding and Synaptogenesis, Cell Specification and Differentiation, Cellular/Molecular/Developmental Neuroscience
Address: JLGSC L3-043
Phone: 212-853-1084
Email: cam4@cumc.columbia.edu
Vilas Menon, PhD
Research Interests: researching the dysregulation of cell types and cell type interactions in neurodegenerative disease, using network-based modeling of transcriptomic data.
Address: PH 19
Phone:
Email: vm2545@cumc.columbia.edu
Cathy Mendelsohn, PhD
Research Interests: Identification of progenitors important for formation and regeneration of the urothelium, Stem cell populations that give rise to bladder cancers, Genetics of lower urinary tract malformations as part of the Columbia University O'Brien Research Center (http://cumcobriencenter.com/), Generating a molecular and cellular atlas of the mouse and human lower urinary tract (https://beta.gudmap.org/tutorials/urogenital-dev/), Role of Pparg in urothelial development, regeneration and bladder cancer
Address: ICRC 311
Phone: 212-851-4781
Email: clm20@cumc.columbia.edu
George Mentis, PhD
Research Interests: Neural Degeneration and Repair, Sensory Physiology, Synapses and Circuits, Motor Systems
Address: P&S 4-450
Phone: 212-305-9846
Email: gzm2002@columbia.edu
Umrao Monani, PhD
Research Interests: Pediatric Neurology, Neurobiology of Disease, Motor Neuron Disease, Synapses and Circuits
Address: P&S 5-422
Phone: 212-342-5132
Email: um2105@columbia.edu
Siddhartha Mukherjee, MD, DPhil
Research Interests: The biology of blood development, in particular, malignant and pre-malignant diseases such as myelodysplasia (MDS) and acute myelogenous leukemia (AML)
Address: ICRC 603
Phone: 212-851-4617
Email: sm3252@columbia.edu
Natura Myeku, PhD
Research Interests: Understanding proteinopathy-induced diseases and their relationship with protein quality control in the cell.
Address: P&S
Phone: 212-304-7884
Email: nm2631@cumc.columbia.edu
Marta Olah, PhD
Research Interests: microglia phenotypes associated with brain plasticity and regeneration
Address: NI
Phone: 000-000-0000
Email: mo2738@cumc.columbia.edu
Kenneth Olive, PhD
Research Interests: Preclinical therapeutics in genetically engineered mouse models of pancreatic cancer
Address: ICRC 217
Phone: 212-851-4678
Email: kenolive@columbia.edu
David Owens, PhD
Research Interests: The contributions of stem cells and differentiated cells to epidermal cancer
Address: Russ Berrie 312A
Phone: 212-851-4544
Email: do2112@cumc.columbia.edu
Teresa Palomero Vazquez, PhD
Research Interests: the genetic and molecular bases of T-cell leukemia and lymphoma, with special interest in the development of targeted therapies for the treatment of these aggressive hematologic tumors
Address: ICRC 401B
Phone: 212-851-4778
Email: tp2151@cumc.columbia.edu
Laura Pasqualucci, MD
Research Interests: Elucidating the genetic basis of mature B cell malignancies, with emphasis on the two most common subtypes, diffuse large B cell lymphoma (DLBCL) and follicular lymphoma (FL)
Address: ICRC 507B
Phone: 212-851-5248
Email: lp171@cumc.columbia.edu
Livio Pellizzoni, PhD
Research Interests: RNA biology, RNA processing, motor neuron biology and diseases, molecular mechanisms of neurodegeneration, synapses and circuits, cellular/molecular/developmental neuroscience
Address: P&S 5-421
Phone: 212-305-3046
Email: lp2284@columbia.edu
Yueqing Peng, PhD
Research Interests: Neurobiology of sleep, Systems and circutis, Epilepsy/psychiatric disorders, Sensory physiology
Address: HHSC 513
Phone: 000-000-0000
Email: yp2249@cumc.columbia.edu
Liza Pon, PhD
Research Interests: Cytosketetal control of organelle movements and segregation during cell division
Address: P&S 14-442
Phone: 212-305-1947
Email: lap5@cumc.columbia.edu
Serge Przedborski, MD, PhD
Research Interests: Neurodegeneration, Neurobiology of Disease, Molecular and Cellular Biology of Neurodegeneration , Parkinson's Disease, Motor Neuron Biology and Diseases, Amyotrophic Lateral Sclerosis, Mitochondria Biology and Disease, Mitophagy, Neuroinflammation, Microglia, Astrocytes, Apoptosis, Necroptosis, Bioinfomatics, High-throughput Screening, Stem Cell Biology, Neural Degeneration and Repair, Motor Systems
Address: P&S 5-420
Phone: 212-342-4119
Email: sp30@cumc.columbia.edu
Li Qiang, PhD
Research Interests: posttranslational modifications (PTMs) of transcription factors in the pathophysiology of diabetes and obesity, and their associated comorbidities, including hepatic steatosis, cancer and cardiovascular diseases.
Address: P&S 16-437
Phone: 212-851-4929
Email: lq2123@cumc.columbia.edu
Jianwen Que, PhD
Research Interests: Molecular and cellular mechanisms controlling proliferation and differentiation of stem/progenitor cells of the foregut
Address: BB 8-810
Phone: 212-305-5961
Email: jq2240@cumc.columbia.edu
Kapil Ramachandran, PhD
Research Interests: a new mechanism of protein degradation in neurons that generates a new form of neuromodulation.
Address: PH 18
Phone: 000-000-0000
Email: kvr2113@cumc.columbia.edu
Kevin Roth, MD, PhD
Research Interests: Neurotransmitter and Neurotrophin Receptors and Cell Signaling , CNS Cancer Biology and Treatment
Address: PH 15W-1564
Phone: 212-305-9134
Email: kar2208@cumc.columbia.edu
Juan Manuel Schvartzman, MD, PhD
Research Interests: understanding how extra- and intra-cellular metabolism regulate chromatin biology
Address: HIP 8th Floor
Phone:
Email: js5279@cumc.columbia.edu
Mimi Shirasu-Hiza, PhD
Research Interests: Neurobiology of Learning and Memory, Neurogenetics, Neural Degeneration and Repair, Cellular/Molecular/Developmental Neuroscience, Circadian-regulated metabolism, Glial development and pathology, Sleep, Mitochondria biology and disease.
Address: HHSC 1602
Phone: 212-305-4011
Email: ms4095@columbia.edu
Janet Sparrow, PhD
Research Interests: Understanding the composition of RPE bisretinoid lipofuscin and conditions modulating its formation, Investigating links between RPE lipofuscin and drusen formation in age-related macular degeneration, Development of therapies to limit RPE lipofuscin formation, Interpretation of patterns of fundus autofluorescence in retinal disorders, Quantitation of fundus autofluorescence intensities
Address: Harkness Eye Institute 701
Phone: 212-305-9944
Email: jrs88@columbia.edu
Steven Spitalnik, MD
Research Interests: The biology of red blood cells
Address: P&S 14-434
Phone: 212-305-2204
Email: ss2479@cumc.columbia.edu
Ira Tabas, PhD
Research Interests: Cellular and molecular processes related to arterial wall biology and atherogenesis
Address: PH 8 East 105F
Phone: 212-305-9430
Email: iat1@columbia.edu
Alison Taylor, PhD
Research Interests: understanding the role of aneuploidy in tumor development.
Address: P&S
Phone:
Email: at3488@cumc.columbia.edu
Andrew Teich, MD
Research Interests: The intersection of systems biology and neurodegenerative disease
Address: P&S 12-420B
Phone: 212-305-2861
Email: aft25@cumc.columbia.edu
Carol Troy, MD, PhD
Research Interests: Neural Degeneration and Repair, Neurobiology of Disease, Regulation of the neurovascular unit
Address: BB 1210C
Phone: 212-305-3119
Email: cmt2@cumc.columbia.edu
Stephen Tsang, MD, PhD
Research Interests: Neural Degeneration and Repair , Stem Cell Biology, Sensory Physiology, Genome Surgery, Gene Therapy
Address: Harkness Eye Institute 513
Phone: 212-342-1189
Email: sht2@columbia.edu
Richard Vallee, PhD
Research Interests: Motor Proteins in Neurogenesis and Neuronal Migration, Stem Cell Biology, Motor Proteins in Axonal Transport, Cellular/Molecular/Developmental Neuroscience, Axon Pathfinding and Synaptogenesis, Neural Degeneration and Repair, Cell Specification and Differentiation
Address: P&S 15-409
Phone: 212-342-0546
Email: rv2025@columbia.edu
Clarissa Waites, PhD
Research Interests: Neural Degeneration and Repair, Cellular/Molecular/Developmental Neuroscience, Neurobiology of Learning and Memory, Synapses and Circuits
Address: BB 1210B
Phone: 212-305-6025
Email: cw2622@columbia.edu
Harris Wang, PhD
Research Interests: Understanding the key principles that drive the formation, maintenance, and evolution of genomes within and across microbial populations
Address: Lasker Building 2-203BB
Phone: 212-305-1697
Email: hw2429@cumc.columbia.edu
Hynek Wichterle, PhD
Research Interests: Neural Degeneration and Repair, Cell Specification and Differentiation, Stem Cell Biology, Cellular/Molecular/Developmental Neuroscience
Address: P&S 14-401G
Phone: 212-342-3929
Email: hw350@cumc.columbia.edu
Howard Worman, MD
Research Interests: Our laboratory is interested in determining how mutations in genes encoding proteins of the inner nuclear membrane cause a wide variety of inherited diseases, including muscular dystrophies, cardiomyopathy, lipodystophy and accelerated aging disorders., We are also intrested in liver diseases, including fatty liver disease and autoimmune liver diseasess such as primary biliary cirrhosis.
Address: P&S 10-508
Phone: 212-305-1306
Email: hjw14@cumc.columbia.edu
Ai Yamamoto, PhD
Research Interests: Roles of macroautophagy in the healthy and diseased CNS, Neural Degeneration and Repair, Disease, Protein trafficking
Address: Black Building 301B
Phone: 212-305-9206
Email: ay46@columbia.edu
Darrell Yamashiro, MD, PhD
Research Interests: Tumor genetics and the design of innovative therapies
Address: Irving Pavilion 7
Phone: 212-305-5808
Email: dy39@columbia.edu
Hee Won Yang, PhD
Research Interests: Cancer biology, Systems biology, Cell biology, Synthetic biology
Address: P&S 14-503
Phone: 212-305-1966
Email: hy2602@cumc.columbia.edu
Andrew Yates, PhD
Research Interests: Integrating theoretical and computational tools with more traditional experimental approaches to study multiple aspects of lymphocyte dynamics
Address: HHSC 310
Phone: 212-305-4035
Email: andrew.yates@columbia.edu
Lori Zeltser, PhD
Research Interests: Cellular/Molecular/Developmental Neuroscience, Sympathetic Innervation of Brown Adipose Tissue, Maternal Programming of Metabolic Disease, Models of Psychiatric Disorders (Anorexia), Circuits Regulating Food Intake and Body Weight
Address: Russ Berrie 628
Phone: 212-851-5314
Email: lz146@columbia.edu
Shan Zha, MD, PhD
Research Interests: The molecular mechanisms of DNA damage response and their roles in lymphocyte gene-rearrangement
Address: ICRC 505A
Phone: 212-851-4779
Email: sz2296@columbia.edu
Xin Zhang, PhD
Research Interests: Mechanism of FGF signaling in eye development, Molecular regulatioin of cell shape, adhesion and migration, Glial development and pathology, Neural degeneration and repair
Address: Harkness Eye Institute 901
Phone: 212-342-4446
Email: xz2369@cumc.columbia.edu
Zhiguo Zhang, PhD
Research Interests: Epigenetic inheritance and Cancer Epigenetics
Address: ICRC 407A
Phone: 212-851-4936
Email: zz2401@cumc.columbia.edu