Muredach Patrick Reilly, MD

Cardiovascular Disease
Accepting New Patients
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Areas of Expertise / Conditions Treated

  • Adult Cardiology
  • Cardiology
  • Disease of Lipid Metabolism
  • Hyperlipidemia
  • Lipid Disorders
  • Lipid Metabolism
  • Preventive Cardiology

Academic Appointments

  • Florence and Herbert Irving Endowed Professor of Medicine

Administrative Titles

  • Director, Irving Institute for Clinical and Translational Research
  • Associate Dean for Clinical and Translational Research
  • Director, Cardiometabolic Precision Medicine Program

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Male

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622 West 168th Street
Room 307
New York, NY 10032

Credentials & Experience

Education & Training

  • MD, University College of Dublin, Faculty of Medicine (Ireland)
  • Internship: St. Vincent's Hospital
  • Residency: University of Pennsylvania Health System
  • Fellowship: University of Pennsylvania Health System

Board Certifications

  • Cardiovascular Disease
America's Top Doctor
NY Top Doctor


As Professor of Medicine at Columbia University, I have experience in human genetics and functional genomics, genetic epidemiology, mechanistic translational research and cardiometabolic medicine. My research program is dedicated to translational genomic studies and focused on (1) cell specific (e.g., adipocyte and macrophage) genomic and transcriptomic contributions to human cardio-metabolic disorders, (2) the functions of adipose tissue in insulin resistance and atherosclerotic risk, (3) novel mechanisms of human atherosclerosis underlying recent GWAS discoveries, (4) the role on innate immunity in promoting cardio-metabolic disease. We employ a translational and genomic approach including human functional genomics, human induced pluripotent stem cell (hiPSC) technology and gene-editing, animal based mechanistic studies, patient-oriented interrogation as well as large scale genetic epidemiological studies. In my role as Director of the Irving Institute for Clinical and Translational Research at Columbia, I also build programs in clinical and translational research and in precision medicine while continuing my research program in cardio-metabolic diseases. I have nearly 20 years in NIH grant funding experience and publications as well as mentorship and teaching activities.